By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Health Works CollectiveHealth Works CollectiveHealth Works Collective
  • Health
    • Mental Health
    Health
    Healthcare organizations are operating on slimmer profit margins than ever. One report in August showed that they are even lower than the beginning of the…
    Show More
    Top News
    mosquito misting spray to fight malaria
    Avoid Malaria with Mosquito Misting Systems
    June 12, 2023
    Medical Surveys
    Beyond the Clinic: Medical Surveys Are a Roadmap to Passive Income for Doctors
    September 23, 2023
    Glutathione
    What Are The Benefits of Glutathione?
    January 22, 2024
    Latest News
    6 Easy Healthcare Ways to Sit Less and Move More Every Day
    September 10, 2025
    7 Most Common Healthcare Accreditation Programs: Which Should You Use?
    August 20, 2025
    Hospital Pest Control and the Fight Against Superbugs
    August 20, 2025
    Hygiene Beyond The Clinic: Attention To Overlooked Non-Clinical Spaces
    August 13, 2025
  • Policy and Law
    • Global Healthcare
    • Medical Ethics
    Policy and Law
    Get the latest updates about Insurance policies and Laws in the Healthcare industry for different geographical locations.
    Show More
    Top News
    Tips for Older Travelers
    April 14, 2012
    Anti-RUC Suit Challenges Process for Setting Doc Pay Scales
    October 25, 2011
    Math Matters: Dosing Errors Can Be Deadly
    May 1, 2012
    Latest News
    Healthcare at a Crossroads: Why Leadership Matters More Than Ever
    September 9, 2025
    How Social Security Disability Shapes Access to Care and Everyday Health
    August 22, 2025
    How a DUI Lawyer Can Help When Your Future Health Feels Uncertain
    August 22, 2025
    How One Fall Can Lead to a Long Road of Medical Complications
    August 22, 2025
  • Medical Innovations
  • News
  • Wellness
  • Tech
Search
© 2023 HealthWorks Collective. All Rights Reserved.
Reading: Big Government Opens Big Database For Cancer Research
Share
Notification Show More
Font ResizerAa
Health Works CollectiveHealth Works Collective
Font ResizerAa
Search
Follow US
  • About
  • Contact
  • Privacy
© 2023 HealthWorks Collective. All Rights Reserved.
Health Works Collective > eHealth > Big Government Opens Big Database For Cancer Research
eHealthNews

Big Government Opens Big Database For Cancer Research

Dan Munro
Dan Munro
Share
4 Min Read
Image
SHARE

Image

(Editor’s Note: Dan Munro writes for Forbes.com under the heading “Healthcare Compass”)

For those of us without degrees in molecular biology, the idea of “personalized medicine” – or PM – can often seem like a vague and distant concept. In this case, the Wikipedia definition of PM is pretty good:

Image

More Read

Population Health Management [INFOGRAPHIC]
Breakthroughs, Back-slapping and Bioluminescence
ET patients featured on ABC World News
HIMSS16 Preview: Data helps reveal theme of this year’s show
Policing The Internet: Physician Behavior In Cyberspace

(Editor’s Note: Dan Munro writes for Forbes.com under the heading “Healthcare Compass”)

For those of us without degrees in molecular biology, the idea of “personalized medicine” – or PM – can often seem like a vague and distant concept. In this case, the Wikipedia definition of PM is pretty good:

Personalized medicine or PM is a medical model that proposes the customization of healthcare – with medical decisions, practices, and/or products being tailored to the individual patient. The use of genetic information has played a major role in certain aspects of personalized medicine, and the term was even first coined in the context of genetics (though it has since broadened to encompass all sorts of personalization measures). To distinguish from the sense in which medicine has always been inherently “personal” to each patient, PM commonly denotes the use of some kind of technology or discovery enabling a level of personalization not previously feasible or practical. Wikipedia.org Definition of Personalized Medicine

According to a press release posted on the American Association for Cancer Research website (here), the National Cancer Institute marked a major milestone earlier this week with the public release of the world’s largest database of cancer related genetic variations.

“To date, this is the largest database worldwide, containing 6 billion data points that connect drugs with genomic variants for the whole human genome across cell lines from nine tissues of origin, including breast, ovary, prostate, colon, lung, kidney, brain, blood, and skin. We are making this data set public for the greater community to use and analyze.This comes at a great time, because genomic medicine is becoming a reality, and I am very hopeful this valuable information will change the way we use drugs for precision medicine.” Yves Pommier, M.D., Ph.D., Chief of the Laboratory of Molecular Pharmacology at the National Cancer Institute in Bethesda, MD

Also from the AACR release was this additional insight:

Pommier and colleagues conducted whole-exome sequencing of the NCI-60 human cancer cell line panel, which is a collection of 60 human cancer cell lines, and generated a comprehensive list of cancer-specific genetic variations. Preliminary studies conducted by the researchers indicate that the extensive data set has the potential to dramatically enhance understanding of the relationships between specific cancer-related genetic variations and drug response, which will accelerate the drug development process.

The data generated in this study provide means to identify new determinants of response and mechanisms of resistance to drugs, and offer opportunities to target genomic defects and overcome acquired resistance, according to Pommier. To enable this, the researchers are making these data available to all researchers via two database portals, called the CellMiner database and the Ingenuity systems database.

While the ability to sequence human genomes has been relatively rapid and increasingly cost-effective, the ability to make sense of the data being created can often take months or even years.

Opening up this database of cancer-specific genetic variations will accelerate the shift from “blockbuster” style drug development (targeted at broad segments) to drugs that are more effective and targeted at small segments – including “markets of one.”

In the broadest sense, that’s a large part of the definition of “personalized medicine” and this weeks significant contribution by the NCI to the global scientific community for accelerating efforts around targeted cancer treatment is great news.

Original Post

TAGGED:big datacancerpersonalized medicine
Share This Article
Facebook Copy Link Print
Share

Stay Connected

1.5kFollowersLike
4.5kFollowersFollow
2.8kFollowersPin
136kSubscribersSubscribe

Latest News

a woman walking on the hallway
6 Easy Healthcare Ways to Sit Less and Move More Every Day
Health
September 9, 2025
Clinical Expertise
Healthcare at a Crossroads: Why Leadership Matters More Than Ever
Global Healthcare
September 9, 2025
travel nurse in north carolina
Balancing Speed and Scope: Choosing the Nursing Degree That Fits Your Goals
Nursing
September 1, 2025
intimacy
How to Keep Intimacy Comfortable as You Age
Relationship and Lifestyle Senior Care
September 1, 2025

You Might also Like

privacy-policy-510731_1920
eHealthPolicy & Law

“What we need is more regulation . . . .”

July 28, 2016
EHR Market Share report
BusinesseHealthMedical Records

Insights from the 2014 Meaningful Use EHR Market Share Report

May 6, 2014

SCOTUS Sets Hearing Dates for ACA Constitutionality; Obama and Romney Weigh Options

November 17, 2011

Patient Care Home Kit With Remote Technology-Video

October 21, 2011
Subscribe
Subscribe to our newsletter to get our newest articles instantly!
Follow US
© 2008-2025 HealthWorks Collective. All Rights Reserved.
  • About
  • Contact
  • Privacy
Welcome Back!

Sign in to your account

Username or Email Address
Password

Lost your password?