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Health Works Collective > Health > What Are the Health Risks of Falsified Drugs?
HealthPolicy & Law

What Are the Health Risks of Falsified Drugs?

Falsified drugs can create a number of very serious health risks, so consumers need to be aware of them.

Aaron Casselman
Last updated: July 15, 2024 8:55 pm
Aaron Casselman
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There are a number of things that we need to do to keep ourselves healthy. One of the most obvious things that you should do is take medication if you are feeling sick.

Contents
Defining the ProblemBad Actors: Intentional MalfeasanceBad Practices: Systemic IssuesThe Interplay Between Bad Actors and Bad PracticesAddressing the Issue: A Comprehensive ApproachConclusion

The first first synthetic drug was chloral hydrate, which was developed in 1869. Since then, many other drugs have reached the market.

The global pharmaceutical market is currently worth $1`.6 trillion, which makes it one of the largest industries in the world. This proves that pharmaceutical drugs are very important for our overall health and well-being.

However, not all drugs are as beneficial for our health as others. In fact, some were released under false pretenses, which creates some very serious health risks.

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The global pharmaceutical industry plays a pivotal role in public health, providing essential medications to millions of people worldwide. However, a growing concern that threatens the integrity of this industry is the proliferation of substandard and falsified drugs. The question at the heart of this issue is whether these substandard or falsified drugs are primarily caused by the actions of bad actors or the result of bad practices within the pharmaceutical supply chain.

Defining the Problem

Substandard drugs are pharmaceutical products that do not meet the quality standards set for them, either due to inadequate manufacturing processes or improper storage and transportation. Falsified drugs, on the other hand, involve intentional misrepresentation, including fake packaging, false labeling, or the presence of incorrect ingredients. The consequences of substandard and falsified drugs are severe, ranging from ineffective treatment to life-threatening complications, making it imperative to identify the root causes of these issues.

Bad Actors: Intentional Malfeasance

One perspective posits that substandard and falsified drugs primarily result from the actions of bad actors within the pharmaceutical supply chain. These bad actors can include criminal organizations, rogue manufacturers, and unscrupulous distributors who intentionally engage in illegal activities to maximize profits. In this scenario, the motivation is clear: financial gain at the expense of public health.

Bad actors often exploit regulatory loopholes, weak enforcement mechanisms, or corruption within regulatory bodies to infiltrate the supply chain. They may produce substandard drugs with subpar ingredients or create counterfeit versions of popular medications, taking advantage of unsuspecting consumers and healthcare providers. This deliberate misconduct raises ethical concerns and necessitates a robust response from regulatory authorities to ensure public safety.

Bad Practices: Systemic Issues

Conversely, another perspective argues that substandard and falsified drugs are primarily the result of systemic issues and bad practices within the pharmaceutical industry. This encompasses a wide range of factors, such as poor manufacturing standards, inadequate quality control, supply chain vulnerabilities, and insufficient operational oversight. These issues can occur at various stages, from the initial production of pharmaceuticals to their distribution and storage.

Manufacturers may cut corners to reduce costs, leading to substandard production processes that compromise the quality of the drugs. Additionally, weaknesses in the supply chain, such as improper storage conditions or lack of traceability, can contribute to the deterioration of medications. Regulatory bodies may also struggle with limited resources or face challenges in adapting to the rapidly evolving landscape of the pharmaceutical industry, allowing substandard and falsified drugs to enter the market.

The Interplay Between Bad Actors and Bad Practices

In reality, the issue of substandard and falsified drugs is not binary but often involves an intricate interplay between intentional malfeasance by bad actors and systemic problems resulting from bad practices. Bad actors may exploit existing vulnerabilities in the system, taking advantage of lapses in manufacturing and distribution processes. Simultaneously, bad practices within the industry create an environment conducive to the illicit activities of these bad actors.

Addressing the Issue: A Comprehensive Approach

Effectively addressing the problem of substandard and falsified drugs requires a multifaceted approach that targets both bad actors and bad practices. Regulatory bodies play a crucial role in strengthening enforcement mechanisms, improving oversight, and closing loopholes that enable criminal activities. Increased collaboration between international organizations, governments, and industry stakeholders is essential to create a unified front against illicit pharmaceutical practices.

Industry stakeholders, including manufacturers, distributors, and healthcare providers, must prioritize quality assurance throughout the entire supply chain. This involves investing in robust manufacturing processes, implementing stringent drug quality control, and enhancing traceability to ensure the authenticity of pharmaceutical products. Embracing technological solutions, such as blockchain and track-and-trace systems, can enhance transparency and accountability in the pharmaceutical supply chain.

Obtaining real-time intelligence that directs remedial action is an essential component of strategies designed to discover and remove SF drugs from the supply chain. Robust solutions must incorporate the testing of products to determine their quality and safety. The targeted introduction of chemical analysis of products provides actionable information for stakeholders, for example to issue alerts, sequester questionable products for further testing, purchase alternative medicines, and monitor patient status, among others.

The ARTiFACTS Verify platform offers an integrated approach to identifying substandard and falsified drugs that have entered the pharmaceutical supply chain:

  • Identification of suspect medicines through on-site testing at any point in the supply chain using paper analytical device technology that is cost-effective and requires minimal training. 
  • Confirmation of the properties of medicines failing the initial test through further testing at specialist labs, using advanced scientifically recognized techniques, including high-performance liquid chromatography, mass spectroscopy, among others.
  • Organisation of all data captured for managing workflows, analysing and reporting results.
  • Coverage of over half of WHO’s 600 Essential Medicines.

Enhanced data security by recording results on a purpose-built blockchain provides an immutable record of test results, including active pharmaceutical ingredients, product origin, manufacturer and other data essential for effective intervention.

Conclusion

In the complex landscape of substandard and falsified drugs, it is essential to recognize the interplay between intentional malfeasance by bad actors and systemic issues stemming from bad practices. A comprehensive and collaborative approach is necessary to safeguard the integrity of the pharmaceutical industry and protect public health. By addressing regulatory gaps, strengthening enforcement, and promoting industry best practices, stakeholders can collectively mitigate the risks associated with substandard and falsified drugs, ensuring that patients receive safe and effective medications.

TAGGED:pharmaceutical
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By Aaron Casselman
Aaron Casselman is a medical writer based in central Minnesota, specializing in bioinformatics. With my Master's Degree in bioinformatics, he brings unique insights into topics related to medicine and health.

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