By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Health Works CollectiveHealth Works CollectiveHealth Works Collective
  • Health
    • Mental Health
    Health
    Healthcare organizations are operating on slimmer profit margins than ever. One report in August showed that they are even lower than the beginning of the…
    Show More
    Top News
    photo of hands with blue veins
    8 Proven Tips on Finding Difficult Veins
    November 12, 2021
    tips for getting over the pandemic blues
    4 Proven Ways to Get Over the Pandemic Blues
    February 22, 2022
    medical industry innovations
    How is CNC Machining Transforming the Medical Industry?
    June 2, 2022
    Latest News
    Grounded Healing: A Natural Ally for Sustainable Healthcare Systems
    May 16, 2025
    Learn how to Renew your Medical Card in West Virginia
    May 16, 2025
    Choosing the Right Supplement Manufacturer for Your Brand
    May 1, 2025
    Engineering Temporary Hospitals for Extreme Weather
    April 24, 2025
  • Policy and Law
    • Global Healthcare
    • Medical Ethics
    Policy and Law
    Get the latest updates about Insurance policies and Laws in the Healthcare industry for different geographical locations.
    Show More
    Top News
    Doctors on Google: Manhattan Research Survey 2012
    July 23, 2012
    HealthCare’s Need for Transparency Goes Far Beyond Pricing
    December 10, 2012
    Medicare Payments to Providers Are Carved, Sliced and Chopped by Sequestration
    March 25, 2013
    Latest News
    Building Smarter Care Teams: Aligning Roles, Structure, and Clinical Expertise
    May 18, 2025
    The Critical Role of Healthcare in Personal Injury Recovery: A Comprehensive Guide for Victims
    May 14, 2025
    The Backbone of Successful Trials: Clinical Data Management
    April 28, 2025
    Advancing Your Healthcare Career through Education and Specialization
    April 16, 2025
  • Medical Innovations
  • News
  • Wellness
  • Tech
Search
© 2023 HealthWorks Collective. All Rights Reserved.
Reading: New Oral Blood Cancer Treatments Bring True Excitement in CLL and CML
Share
Notification Show More
Font ResizerAa
Health Works CollectiveHealth Works Collective
Font ResizerAa
Search
Follow US
  • About
  • Contact
  • Privacy
© 2023 HealthWorks Collective. All Rights Reserved.
Health Works Collective > Specialties > New Oral Blood Cancer Treatments Bring True Excitement in CLL and CML
Specialties

New Oral Blood Cancer Treatments Bring True Excitement in CLL and CML

Andrew Schorr
Last updated: December 16, 2012 1:30 pm
Andrew Schorr
Share
4 Min Read
SHARE

Is chemo dead? Maybe not yet, but in some diseases it is fading fast. In 2000 I was one of the early patients to receive FCR for chronic lymphocytic leukemia (CLL) in a phase II trial, and thousands have followed. The F and the C are chemotherapies and they are not kind to your body. Many patients, including me, have received a long remission and we are, of course, very grateful. But others have not done nearly as well. So the search for better, less toxic cancer treatments has continued.

Is chemo dead? Maybe not yet, but in some diseases it is fading fast. In 2000 I was one of the early patients to receive FCR for chronic lymphocytic leukemia (CLL) in a phase II trial, and thousands have followed. The F and the C are chemotherapies and they are not kind to your body. Many patients, including me, have received a long remission and we are, of course, very grateful. But others have not done nearly as well. So the search for better, less toxic cancer treatments has continued. Now the research appears to be paying off.

As we reported from the very recent ASH (American Society of Hematology) meeting in Atlanta, CLL leaders like Dr. John Byrd from Ohio State and Jan Burger from MD Anderson were extremely pleased with results from clinical trials of Ibrutinib, a targeted oral therapy, for a wide range of patients, including some with the most difficult to treat forms of the disease. Dr. Byrd was truly excited and other CLL doctors, observing the results, see a new, non-chemo day coming very soon for CLL. Other drugs, most of them pills one can take at home, show great promise, as well.

The excitement doesn’t stop with CLL. A drug that had been known as ponatinib for chronic myelogenous leukemia (CML) was also reported as a breakthrough medicine. Again, this was a targeted oral therapy, best known for helping CML patients with the resistant T315i mutation, but also seen as a more powerful agent for people with other forms of resistance.

More Read

dental restoration
The Future of Dental Restoration: 7 Innovative Techniques
Angelina Jolie’s Decision: Do I Need to Be Tested?
How Technology Shapes Dentistry’s Future
Ways to Manage the Health Implications of Financial Stress
What Are the Advantages of Teeth Whitening to Treat Discoloration?

We knew this was big news and was expected to be the validation the FDA needed to give the drug accelerated approval early in 2013. But the FDA, criticized in the past for slow approvals, was watching too, and only days after the news conference at ASH the FDA approved the drug, which now has the brand name of Iclusig.

A Seattle family is very familiar with these developments. Hans Loland entered a Phase I trial after it was discovered that he had the rare T315i mutation, which rendered the standard, approved therapies ineffective. Hans already was familiar with the disease because his best friend had also been diagnosed with CML just months before. The trial showed signs of success, giving Hans and his wife the confidence to have the third child (Cooper) they had always wanted, as he shared in his Powerful Patient video.

Given that there are now six approved and effective treatments for CML you can expect tremendous chatter about which patient should receive which drug, when, and for how long. Stay tuned, as we are committed to following this and other developments closely. Be sure to be signed up for our alerts for the condition that’s most important to you or your loved one so that you can stay informed of these developments with us.

Wishing you and your family the best of health!

Andrew

TAGGED:cancerpharmacology
Share This Article
Facebook Copy Link Print
Share

Stay Connected

1.5kFollowersLike
4.5kFollowersFollow
2.8kFollowersPin
136kSubscribersSubscribe

Latest News

Clinical Expertise
Building Smarter Care Teams: Aligning Roles, Structure, and Clinical Expertise
Health care
May 18, 2025
Grounded Healing: A Natural Ally for Sustainable Healthcare Systems
Grounded Healing: A Natural Ally for Sustainable Healthcare Systems
Health
May 15, 2025
Learn how to Renew your Medical Card in West Virginia
Learn how to Renew your Medical Card in West Virginia
Health
May 15, 2025
Dr. Klaus Rentrop Shares Acute Myocardial Infarction heart treatment
Dr. Klaus Rentrop Shares Acute Myocardial Infarction
Cardiology
May 13, 2025

You Might also Like

eHealthSpecialtiesWellness

How To Look For A Drug Addiction Treatment Center

May 13, 2019
rare diseases
eHealthSpecialtiesTechnology

Hacking the Diagnosis of Rare Diseases

December 19, 2013
Geriatrics

Oh, My Aching Joints

July 22, 2012
best sofas for back support
OrthopaedicsSpecialties

Best Sofas for Back Support & Relief from Bad Back Pain

August 18, 2021
Subscribe
Subscribe to our newsletter to get our newest articles instantly!
Follow US
© 2008-2025 HealthWorks Collective. All Rights Reserved.
  • About
  • Contact
  • Privacy
Welcome Back!

Sign in to your account

Username or Email Address
Password

Lost your password?