By using this site, you agree to the Privacy Policy and Terms of Use.
Accept
Health Works CollectiveHealth Works CollectiveHealth Works Collective
  • Health
    • Mental Health
    Health
    Healthcare organizations are operating on slimmer profit margins than ever. One report in August showed that they are even lower than the beginning of the…
    Show More
    Top News
    bowl of vegetable salad
    Raw Foods: benefits and harms
    November 9, 2021
    pros and cons of the keto diet
    Read This Before You Follow the Keto Diet
    May 18, 2022
    spinal cord injuries
    4 Potential Causes of Spinal Cord Injuries (and How to Seek Compensation)
    May 25, 2022
    Latest News
    Grounded Healing: A Natural Ally for Sustainable Healthcare Systems
    May 16, 2025
    Learn how to Renew your Medical Card in West Virginia
    May 16, 2025
    Choosing the Right Supplement Manufacturer for Your Brand
    May 1, 2025
    Engineering Temporary Hospitals for Extreme Weather
    April 24, 2025
  • Policy and Law
    • Global Healthcare
    • Medical Ethics
    Policy and Law
    Get the latest updates about Insurance policies and Laws in the Healthcare industry for different geographical locations.
    Show More
    Top News
    4 Reasons Why Medical Device Compliance Matters
    May 22, 2020
    What To Know About The Importance Of Healthcare Marketing
    November 23, 2019
    healthcare courses
    6 Supplemental Courses in Healthcare to Support Your HR Degree
    August 20, 2021
    Latest News
    Building Smarter Care Teams: Aligning Roles, Structure, and Clinical Expertise
    May 18, 2025
    The Critical Role of Healthcare in Personal Injury Recovery: A Comprehensive Guide for Victims
    May 14, 2025
    The Backbone of Successful Trials: Clinical Data Management
    April 28, 2025
    Advancing Your Healthcare Career through Education and Specialization
    April 16, 2025
  • Medical Innovations
  • News
  • Wellness
  • Tech
Search
© 2023 HealthWorks Collective. All Rights Reserved.
Reading: The Technology Corner: Disruptive Technology for Prostate Cancer, Part I
Share
Notification Show More
Font ResizerAa
Health Works CollectiveHealth Works Collective
Font ResizerAa
Search
Follow US
  • About
  • Contact
  • Privacy
© 2023 HealthWorks Collective. All Rights Reserved.
Health Works Collective > Specialties > The Technology Corner: Disruptive Technology for Prostate Cancer, Part I
Specialties

The Technology Corner: Disruptive Technology for Prostate Cancer, Part I

HerinaAyot
Last updated: May 17, 2012 7:42 am
HerinaAyot
Share
6 Min Read
SHARE

In this special series we present emerging technologies which hold the promise to significantly improve the prognosis of patients diagnosed with prostate cancer, and cancer in general. Each day we will showcase a new emerging company, providing an eloquently detailed description of the intriguing technology.

In this special series we present emerging technologies which hold the promise to significantly improve the prognosis of patients diagnosed with prostate cancer, and cancer in general. Each day we will showcase a new emerging company, providing an eloquently detailed description of the intriguing technology. The goal of this series is to deeply investigate the unique technology that may soon change the mainstream approach to prostate cancer. At the end of the week, we will publish all treatments together.

*************************

The prostate is a component of the male exocrine gland system that is essential for normal reproductive function. Secretory fluid produced by the prostate physiologically supports male gamete cells to successfully achieve conception 1.

More Read

Image
Schmoozing for Cancer, Part II
5 Sobering Statistics About Treating PPD
Everything You Need To Know About Dental X-Rays And 3D Imaging
Gustavo Cordon: A Master in Dental Prosthetics
Massive Health Benefits of Ear Pinning as Solutions to Bullying Epidemic

In medicine, prostate cancer is the most common cancer found in the male population, afflicting one in six men. It is the second leading cause of cancer-based deaths amongst men in the US 2,3. Malignancy of the prostate has profound health consequences, including urinary dysfunction, pelvic pain, and erectile dysfunction 4-6. The disease rarely presents under the age of 40, making age the most significant risk factor – the longer life expectancy of men and the high morbidity/mortality observed makes prostate-cancer a high need condition.

Although there are several treatment options available for patients diagnosed with progressive prostate cancer, the currently used modalities of treatment have important limitations 7,8.

Surgical intervention – such as prostatectomy – comes with the normal risks associated with surgery, as well as the possibility of resultant erectile and urinary dysfunction.

Radiotherapy such as XRT (external radiation therapy) and brachytherapy provide localized radiation to the prostate that can salvage surrounding healthy tissue, but is often associated with urinary urgency and frequency, painful urination, and rectal inflammation.

Androgen deprivation hormone therapy, which includes the newly approved drug Abiraterone, provides a pivotal treatment regimen to inhibit the progression of advanced prostate cancer, but results in serious side effects that include cardiovascular disease, osteoporosis, cognitive deficits, and insulin resistance.

Chemotherapy, which includes the newly approved drug cabazetaxel, is important for treating refractory prostate cancer, but does not salvage healthy tissue and includes significant side effects, such as blood cell suppression and peripheral neuropathy.

Therefore, there remains a high-need for a broad-based therapeutic regimen to treat prostate cancer with minimal side effects.

*************************

Apovax Inc. is a biotechnology company that has developed a powerful therapeutic-protein platform that modulates the patient’s immune system in order to treat diseases. Depending on the goal of these therapies, the company’s products can either up-regulate or down-regulate the immune system to obtain the desired therapeutic outcome. In the latter case, the therapeutic protein is able to mount an immune response against an infectious disease or particular cancer.

At the core of Apovax’s immunological-stimulating technology is a chimeric protein with dual characteristic properties: a streptavidin protein segment that enables aggregation of these proteins into tetramers and an immuno-regulatory protein segment that can bind to immune cells and activate them. This design not only enables these therapeutic proteins (self termed Apovax) to bind the immune cells, but also to aggregate into a complex upon binding, which is required for obtaining a maximal immune response. Conventionally-used protein methodologies that bind to immune cells to activate them lack the capabilities of aggregating into complexes and therefore only achieve a weak stimulation of the immune system. These Apovax proteins are then combined with a disease-specific marker, or antigen, to comprise the complete therapy that produces a strong immune system response against the specified disease.

Apovax is currently developing its platform to treat cervical cancer, colon cancer and prostate cancer. Pre-clinical studies have shown that Apovax is far more effective and less toxic than counter part vaccine technologies currently in clinical trials, including agonistic antibodies. Furthermore, studies have shown that while Apovax generates a potent immune response, it also suppresses a specific component of the immune system known as T-regulatory cells that confer tumors with the ability to evade the immune system. T-regulatory cells shut down normal immune defense in the tumor microenvironment making them an immune privileged, and Apovax’s capability to suppress this action give it a considerable advantage as a therapeutic cancer treatment. The company is utilizing its Apovax technology in conjunction with the hallmark PSA prostate cancer antigen indicated for the treatment of prostate cancer.

 

TAGGED:cancerprostate cancer
Share This Article
Facebook Copy Link Print
Share

Stay Connected

1.5kFollowersLike
4.5kFollowersFollow
2.8kFollowersPin
136kSubscribersSubscribe

Latest News

Do You Grind Your Teeth at Night? Here’s How Night Guards and TMJ Treatments Can Help
Do You Grind Your Teeth at Night? Here’s How Night Guards and TMJ Treatments Can Help
Dental health
May 21, 2025
The Secret To A Confident Smile: Top Tips For Better Teeth
The Secret To A Confident Smile: Top Tips For Better Teeth
Dental health
May 21, 2025
Clinical Expertise
Building Smarter Care Teams: Aligning Roles, Structure, and Clinical Expertise
Health care
May 18, 2025
Grounded Healing: A Natural Ally for Sustainable Healthcare Systems
Grounded Healing: A Natural Ally for Sustainable Healthcare Systems
Health
May 15, 2025

You Might also Like

LifeLongHealth.com – A Health-Oriented Social Network for Baby Boomers

October 13, 2012
oral health of child
Dental health

5 Ways Poor Oral Health Affects a Child’s Well-Being

December 28, 2021
SpecialtiesTechnologyWellness

Fighting Addiction: Neuro Rehabilitative Treatment Offers New Hope with Better Diagnostics

July 3, 2017
obesity and cancer
Specialties

The Obesity-Cancer Connection

September 2, 2013
Subscribe
Subscribe to our newsletter to get our newest articles instantly!
Follow US
© 2008-2025 HealthWorks Collective. All Rights Reserved.
  • About
  • Contact
  • Privacy
Welcome Back!

Sign in to your account

Username or Email Address
Password

Lost your password?